Rajashree Pandit

Rajashree Pandit

M.D.

Assistant Professor, Clinical Skills III & IV

Biography:

Courses: System & Disease III and IV; Clinical Skills II, III, IV, V; Med 918; RLRA

“One never notices what has been done; one can only see what remains to be done”….Marie Curie 

Dr. Rajashree Pandit graduated from Jawaharlal Institute of Postgraduate Medical Education and Research, (JIPMER) Pondicherry, University of Madras, and  gained Residency experience in General Surgery at the University of Washington in Seattle , and at PGIMER, Chandigarh. She has many years of training and experience in clinical medicine and the basic sciences from top-notch universities in the US and India. In addition, she did  extensive research at Duke University Medical Center. 

Dr. Pandit did graduate work in Clinical Biochemistry at JIPMER, and worked in renowned hospitals like GB Pant (Neurosurgery) and RML Hospital (Surgery), University of Delhi, and Rajiv Gandhi Cancer institute (Oncology).  

About 20 years ago Dr. Pandit came to the US for a Visiting Scholarship in Trauma at Harborview Medical Center in Seattle. She went on to do a 2-year Preliminary Surgery Residency at the University of Washington. Her rotations in different specialties like Cardiothoracic and Vascular, Abdominal Transplant, Plastic surgery, Orthopedics, and in various environments like the University Hospital, the ER as Trauma Doc, and the VA hospital, added to her experience in clinical practice. Subsequently, she did research in the lab of the Chairman, Department of Surgery, at Duke University.  While at Duke she later worked in clinical research in Heart Transplant Surgery, participating in acquiring and processing Heart explants and related research projects. She was part of a team that generated publications in major journals, including one in Scientific Reports (Nature). 

At SUSOM, in Systems and Disease, she has taught Cardiovascular, Hematological, Pulmonary, Endocrine, Renal, Musculoskeletal, among other systems which are primarily lecture-based. She regularly teaches Clinical Skills across all organ systems, and clinical sessions and workshops in small and large groups.

In addition to my professional life, I am blessed with a wonderful and supportive family. I have volunteered extensively and like to be involved in community events. 


  • Surgery
  • Cardiovascular Medicine
  • Heart Transplantation
  • Medical Education
 
  • USMLE certified; completed all the Steps of the USMLE 
  • Medical License WA and FL 
  • NTSE scholar 
  • Santacruz L, Arciniegas AJL,DarrabieM, Mantilla JG, Baron RM, Bowles DE, Mishra R, Jacobs DO. Hypoxia decreases creatine uptake in cardiomyocytes, while creatine supplementation enhances HIF activation. Physiol Rep. 2017 Aug;5(16). pii: e13382. doi: 10.14814/phy2.13382. PubMed ID: 28821596.
  • Feger BJ, Thompson JW, Dubois LG,KommaddiRP, Foster MW, Mishra R, Shenoy SK, Shibata Y, Kidane YH, Moseley MA, Carnell LS, Bowles DE.  Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection. Science  Reports. 2016 Sep 27;6:34091. doi: 10.1038/srep34091. PubMed ID: 27670941. 
  • Schechter MA, Watson MJ, Feger BJ, Southerland KW, Mishra R, Dibernardo LR,Kuchibhatla M, Schroder JN, Daneshmand MA, Patel CB, Rogers JG, Milano CA, Bowles DE. Elevated cardiac troponin i in preservation solution is associated with primary graft dysfunction. J Card Fail. 2016 Feb;22(2):158-62. doi: 10.1016/j.cardfail.2015.08.339. PubMed ID: 26365053. 
  • Santacruz L,Darrabie MD, Mantilla JG, Mishra R, Feger BJ, Jacobs DO. Creatine supplementation reduces doxorubicin-induced cardiomyocellular injury. Cardiovasc Toxicol. 2015 Apr;15(2):180-8. doi: 10.1007/s12012-014-9283-x. PubMed ID: 25253560. 
  • Santacruz L,Darrabie MD, Mishra R, Jacobs DO. Removal of potential phosphorylation sites does not alter creatine transporter response to PKC or substrate availability. Cell Physiol Biochem. 2015;37(1):353-60. doi: 10.1159/000430359. PubMed ID: 26316082. 
  • Santacruz L, Hernandez A, Nienaber J, Mishra R, Pinilla M, Burchette J, Mao L, Rockman HA, Jacobs DO. Normal cardiacfunction in mice with supraphysiological cardiac creatine levels. Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H373-81. doi: 10.1152/ajpheart.00411.2013. PubMed ID: 24271489. 
  • Darrabie MD, Arciniegas AJ, Mantilla JG, Mishra R, Vera MP, Santacruz L, Jacobs DO. Exposing cardiomyocytes to subclinical concentrations of doxorubicin rapidly reduces their creatine transport. Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H539-48. doi: 10.1152/ajpheart.00108.2012. PubMed ID: 22752631. 
  • Darrabie MD, Arciniegas AJ, Mishra R, Bowles DE, Jacobs DO, Santacruz L. AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes. Am J Physiol Endocrinol Metab. 2011 May;300(5):E870-6. doi: 10.1152/ajpendo.00554.2010. PubMed ID: 21364119. 
  • Transporters
  • Viral generation
  • Molecular biology
  • SNP 
  • Genotyping
  • Specialized cardiovascular cell culture
  • Animal studies
  • Conference on Fragility Fracture Network in Oxford, UK, August 2019 
  • Conferences on Cardiovascular Medicine and Surgery, Duke University 
  • Posters in Conference of Black Association of Surgeons,  2011 and 2012 
Other Departments